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KMID : 0378019940370090082
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New Medical Journal
1994 Volume.37 No. 9 p.82 ~ p.86
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A Clinical Effects of Flomoxef on Postoperative Infection in the Field of Surgery
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Abstract
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Flomoxef, a new oxacephem antibiotic which has a broad antibacterial activity against Gram positive, Gram negative, Anaerobic bacteria and methicillin resistant Staphylococcus aureus (MRSA), was administered to 15 patients with surgical infection, including 5 with perforated appendicitis and intestinal perforation or periappendicular abscess, 7 with GB empyema and cholecystitis or cholangitis, 3 with stomach cancer and right colon cancer from- May to Aug. 1993.
The results were as follow
1. Flomoxef was administered intravenously 2g. a day for 5-11 days.
2. The clinical effects of Flomoxef on surgical field were excellent in 6, good in 8, fair in 1 patient, the overall efficacy being 93% (14 of 15 patients).
3. Side effect occurred in 1 case but not serious and in the laboratory finding, elevating of GPT in 1 case.
Therefore, Flomoxef was thought to be one of the most effective antibiotics on surgical field.
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